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Organization of Two Independent Kisspeptin Systems Derived from Evolutionary-Ancient Kiss Genes in the Brain of Zebrafish

16 Feb 2011

Abstract excerpt

Kisspeptins are new actors in the neuroendocrine regulation of reproduction. In vertebrates, the number of kiss genes varies from none to three. Zebrafish have two kiss genes, kiss1 and kiss2, and two kiss receptors (GPR54), kiss1r and kiss2r. To provide detailed information on the organization of the kiss systems in zebrafish, antibodies were raised against the C terminus of zebrafish preproKiss1 and...

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PMID: 21325050
DOI: 10.1210/en.2010-0948

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