Article
An unusual BRCA mutation distribution in a high risk cancer genetics clinic.
Familial cancer - 1 Mar 2013
Nelson-Moseke Anna C, Jeter Joanne M, Cui Haiyan, Roe Denise J, Chambers Setsuko K, Laukaitis Christina M
Abstract excerpt
The Database of Individuals at High Risk for Breast, Ovarian, or Other Hereditary Cancers at the Arizona Cancer Center in Tucson, Arizona assesses cancer risk factors and outcomes in patients with a family history of cancer or a known genetic mutation. We analyzed the subset of clinic probands who carry deleterious BRCA gene mutations to identify factors that could explain why mutations in BRCA2 outnumber those...
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