Insulin resistance does not affect early embryo development but lowers implantation rate in <i>in vitro</i> maturation–<i>in vitro</i> fertilization–embryo transfer cycle

Abstract excerpt

OBJECTIVE: Although extensive evidence indicates the hyperinsulinemia directly contributes to reproductive dysfunction in polycystic ovarian syndrome (PCOS), influence of insulin resistance (IR) on assisted reproductive technology outcomes is poorly understood. In this study we aimed to evaluate the effects of IR on in vitro maturation-in vitro fertilization-embryo transfer (IVM-IVF-ET) in patients with PCOS....

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