Article
GSTM1 polymorphism modifies the effect of smoking on calcaneal quantitative ultrasound in young men.
Molecular medicine reports - 1 Feb 2013
Liu Tao, Sun Xuechuan, Zhuang Xiao, Liang Jingqun
Abstract excerpt
Evidence suggests that smoking adversely affects bones. Glutathione S-transferases (GSTs) are important in the detoxification of tobacco smoke compounds. This study investigated the influence of GSTM1 and GSTT1 genetic polymorphisms on the effects on bone induced by tobacco smoking in young men. In total, 231 Chinese men aged 20-39 years were assessed by a cross-sectional study. Calcaneal quantitative ultrasound...
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