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Article

Molecular cloning, characterization and differential expression of DRK1 in Sporothrix schenckii

22 Nov 2012

Abstract excerpt

The dimorphism of Sporothrix schenckii (S. schenckii) reflects a developmental switch in morphology and lifestyle that is necessary for virulence. DRK1, a hybrid histidine kinase, functions as a global regulator of dimorphism and virulence in Blastomyces dermatitidis (B. dermatitidis) and Histoplasma capsulatum (H. capsulatum). The partial cDNA sequence of DRK1 of S. schenckii, designated SsDRK1, was obtained...

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PMID: 23175272
DOI: 10.3892/ijmm.2012.1193

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