Article
High-throughput microbial population genomics using the Cortex variation assembler.
Bioinformatics (Oxford, England) - 15 Jan 2013
Iqbal Zamin, Turner Isaac, McVean Gil
Abstract excerpt
SUMMARY: We have developed a software package, Cortex, designed for the analysis of genetic variation by de novo assembly of multiple samples. This allows direct comparison of samples without using a reference genome as intermediate and incorporates discovery and genotyping of single-nucleotide polymorphisms, indels and larger events in a single framework. We introduce pipelines which simplify the analysis of...
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