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Article

Candidate gene linkage approach to identify DNA variants that predispose to preterm birth.

Pediatric research - 1 Feb 2013

Bream Elise N A, Leppellere Cara R, Cooper Margaret E, Dagle John M, Merrill David C, Christensen Kaare, Simhan Hyagriv N, Fong Chin-To, Hallman Mikko, Muglia Louis J, Marazita Mary L, Murray Jeffrey C

Abstract excerpt

BACKGROUND: The aim of this study was to identify genetic variants contributing to preterm birth (PTB) using a linkage candidate gene approach. METHODS: We studied 99 single-nucleotide polymorphisms (SNPs) for 33 genes in 257 families with PTBs segregating. Nonparametric and parametric analyses w...

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Source

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Identifiers

PMID: 23168575
DOI: 10.1038/pr.2012.166
PMCID: PMC3740714

Genes

CRHR1
TRAF2
DHCR7
ENPP1
IGFBP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23168575-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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