Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Viperin restricts chikungunya virus replication and pathology

19 Nov 2012

Abstract excerpt

Chikungunya virus (CHIKV) is a mosquito-borne arthralgia arbovirus that is reemergent in sub-Saharan Africa and Southeast Asia. CHIKV infection has been shown to be self-limiting, but the molecular mechanisms of the innate immune response that control CHIKV replication remain undefined. Here, longitudinal transcriptional analyses of PBMCs from a cohort of CHIKV-infected patients revealed that type I IFNs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to interferon and immune responses
Share to Mosquito-borne diseases and control
Share to Viral Infections and Vectors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23160199
DOI: 10.1172/jci63120

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Viperin restricts chikungunya virus replication and pathologyPMID 23160199Read ↗

Single-Cell Transcriptomic Analysis of the Immune Response to CHIKV InfectionSemantic proximity Read ↗

Evolution and immunopathology of chikungunya virus informs therapeutic development.Semantic proximity Read ↗

The Interferon Inducible Gene: ViperinSemantic proximity Read ↗

The Role of Viperin in the Innate Antiviral ResponseSemantic proximity Read ↗

Viperin Restricts Zika Virus and Tick-Borne Encephalitis Virus Replication by Targeting NS3 for Proteasomal DegradationSemantic proximity Read ↗

Chikungunya virus persists in joint associated macrophages and promotes chronic diseaseSemantic proximity Read ↗

From Infection to Inflammation: A Transcriptome-Wide Analysis of CHIKV Impact on Primary Human Skeletal Muscle CellsSemantic proximity Read ↗

The Role of Viperin in Antiflavivirus ResponsesSemantic proximity Read ↗

Single-cell transcriptomic analysis of antiviral responses and viral antagonism in Chikungunya virus-infected synovial fibroblastsSemantic proximity Read ↗

Viperin Is Induced following Dengue Virus Type-2 (DENV-2) Infection and Has Anti-viral Actions Requiring the C-terminal End of ViperinSemantic proximity Read ↗

Viperin is an important host restriction factor in control of Zika virus infectionSemantic proximity Read ↗

Viperin, a key player in the antiviral responseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.