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Article

Pathways to age of onset of heroin use: a structural model approach exploring the relationship of the COMT gene, impulsivity and childhood trauma.

PloS one - 1 Jan 2012

Li Ting, Du Jiang, Yu Shunying, Jiang Haifeng, Fu Yingmei, Wang Dongxiang, Sun Haiming, Chen Hanhui, Zhao Min

Abstract excerpt

BACKGROUND: The interaction of the association of dopamine genes, impulsivity and childhood trauma with substance abuse remains unclear. OBJECTIVES: To clarify the impacts and the interactions of the Catechol -O-methyltransferase (COMT) gene, impulsivity and childhood trauma on the age of onset of heroin use among heroin dependent patients in China. METHODS: 202 male and 248 female inpatients who meet DSM-IV...

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Source

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Identifiers

PMID: 23155402
DOI: 10.1371/journal.pone.0048735
PMCID: PMC3498242

Genes

COMT

Provenance

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