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Article

Screening for and verification of novel mutations associated with drug resistance in the HIV type 1 subtype B(') in China.

PloS one - 1 Jan 2012

Li Hanping, Geng Qingmao, Guo Wei, Zhuang Daomin, Li Lin, Liu Yongjian, Bao Zuoyi, Liu Siyang, Li Jingyun

Abstract excerpt

OBJECTIVE: Mutations associated with HIV drug resistance have been extensively characterized at the HIV-1 polymerase domain, but more studies have verified that mutations outside of the polymerase domain also results in resistance to antiviral drugs. In this study, mutations were identified in 354 patients experiencing antiretroviral therapy (ART) failure and in 97 naïve-therapy patients. Mutations whose impact...

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Share to Amino Acid Sequence
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23144802
DOI: 10.1371/journal.pone.0047119
PMCID: PMC3493567

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