Article
Cancer stem cells and tumor dormancy.
Advances in experimental medicine and biology - 1 Jan 2013
Enderling Heiko
Abstract excerpt
The cancer stem cell hypothesis postulates that only a subpopulation of cancer cells in a tumor is capable of initiating, sustaining, and reinitiating tumors, while the bulk of the population comprises non-stem cancer cells that lack tumor initiation potential. The interactions of these two phenotypically distinct populations can provoke various nonlinear growth kinetics in the emerging tumor. An environmentally...
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