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Article

Potential of primary kidney cells for somatic cell nuclear transfer mediated transgenesis in pig

9 Nov 2012

Abstract excerpt

BACKGROUND: Somatic cell nuclear transfer (SCNT) is currently the most efficient and precise method to generate genetically tailored pig models for biomedical research. However, the efficiency of this approach is crucially dependent on the source of nuclear donor cells. In this study, we evaluate the potential of primary porcine kidney cells (PKCs) as cell source for SCNT, including their proliferation capacity,...

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PMID: 23140586
DOI: 10.1186/1472-6750-12-84

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