Article
Identification of a novel human leukocyte antigen allele B∗46:34.
Human immunology - 1 Feb 2013
Shen Chun-mei, Wang Hong-dan, Deng Ya-jun, Wang Shi-ying, Zhang Li-ping, Zhang Bo, Pu Hong-wei, Wu Qiang-ju, Liu Wen-juan, Zhu Bo-feng
Abstract excerpt
A new human leukocyte antigen (HLA) B allele was found in a healthy male Chinese Kazak individual. Sequencing-based typing (SBT) was used to identify and analyze the difference between the new allele and the closest matching HLA-B allele. HLA-B(∗)46 new allele has 1nt change from B(∗)46:01:01 at nt 853 where G->C (condon 260 GTA->CTA), resulting in a coding change: 260 Val is changed to Leu. The new HLA-B(∗)46:34...
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