Article
Norcantharidin suppresses cell growth and migration with enhanced anticancer activity of gefitinib and cisplatin in human non-small cell lung cancer cells.
Oncology reports - 1 Jan 2013
Lee Ya-Chun, Lee Liang-Ming, Yang Chih-Hsin, Lin Anya Maan-Yuh, Huang Yi-Chia, Hsu Chia-Chi, Chen Meng-Shian, Chi Chin-Wen, Yin Pen-Hui, Kuo Cheng-Deng, Liao Jyh-Fei, Lee Hsin-Chen
Abstract excerpt
Norcantharidin is the demethylated analog of cantharidin isolated from blister beetles (Mylabris phalerata Pall.). In this study, we evaluated whether norcantharidin exhibits anticancer effects against the human non-small cell lung cancer cell lines A549 (epidermal growth factor receptor (EGFR) mutation-negative) and PC9 (EGFR mutation-positive). Our results...
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