Article
CNTNAP2 is significantly associated with schizophrenia and major depression in the Han Chinese population.
Psychiatry research - 30 May 2013
Ji Weidong, Li Tao, Pan Yaosheng, Tao Hua, Ju Kang, Wen Zujia, Fu Yingchun, An Zhiguo, Zhao Qian, Wang Ti, He Lin, Feng Guoyin, Yi Qizhong, Shi Yongyong
Abstract excerpt
CNTNAP2, located on 7q35-36.1, encodes a single-pass transmembrane protein mediating cell-cell interactions in the nervous system. CNTNAP2 has been suggested to play an important role in mental diseases such as autism and language disorder. However, we still do not know whether it also confers risk to major psychiatric disorders such as schizophrenia, major depression and bipolar disorder. We analysed single...
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