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Article

Parkinson disease is not associated with C9ORF72 repeat expansions.

Neurobiology of aging - 1 May 2013

Harms Matthew B, Neumann Drexel, Benitez Bruno A, Cooper Breanna, Carrell David, Racette Brad A, Perlmutter Joel S, Goate Alison, Cruchaga Carlos

Abstract excerpt

Hexanucleotide expansions in the C9ORF72 gene are frequently found in patients with amyotrophic lateral sclerosis, frontotemporal dementia or both, some of whom exhibit concurrent extrapyramidal symptoms. To determine if repeat expansions are a cause of Parkinson's disease (PD), we used repeat-primed polymerase chain reaction to investigate the frequency of C9ORF72 repeat expansions in a cohort of 478 patients...

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Identifiers

PMID: 23116878
DOI: 10.1016/j.neurobiolaging.2012.10.001
PMCID: PMC3566343

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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