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Article

Inefficient vaginal transmission of tenofovir-resistant HIV-1.

Journal of virology - 1 Jan 2013

Chateau Morgan, Swanson Michael D, Garcia J Victor

Abstract excerpt

Transmission of drug-resistant HIV has been postulated to be a threat to current first-line antiretroviral therapy (ART) regimens and the efficacy of several antiretroviral-based preexposure prophylaxis (PrEP) strategies being tested. Here we evaluated the effect of the common tenofovir (TFV) resistance mutation K65R on vaginal HIV transmission. Our results demonstrate that despite no overt loss of overall...

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Identifiers

PMID: 23115295
DOI: 10.1128/JVI.01777-12
PMCID: PMC3554084

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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