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Exosomes and the kidney: Blaming the messenger

1 Nov 2012

Abstract excerpt

Exosomes are membrane-bound vesicles of endosomal origin, present in a wide range of biological fluids, including blood and urine. They range between 30 and 100 nm in diameter, and consist of a limiting lipid bilayer, transmembrane proteins and a hydrophilic core containing proteins, mRNAs and microRNAs (miRNA). Exosomes can act as extracellular vehicles by which cells communicate, through the delivery of their...

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PMID: 23113949
DOI: 10.1111/nep.12005

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