Nonsense suppressors partially revert the decrease of the mRNA level of a nonsense mutant allele in yeast.

doi:10.1007/BF00313252

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Article

Nonsense suppressors partially revert the decrease of the mRNA level of a nonsense mutant allele in yeast.

Current genetics - 1 Jan 1990

Gozalbo D, Hohmann S

Abstract excerpt

suc2 degrees is a naturally occurring amber mutant allele of the yeast invertase structural gene SUC2. Strains carrying suc2 degrees had only 10% of the wild type invertase-specific mRNA level. Amber suppressors, which allowed suc2 degree strains to ferment sucrose caused an increase of the SUC-s...

Topics

Alleles
Blotting, Northern
Genes, Fungal
Glycoside Hydrolases
Mutation
RNA, Fungal
RNA, Messenger
Suppression, Genetic
Transformation, Genetic
Yeasts
beta-Fructofuranosidase

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