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The Dynamics of the Mitochondrial Organelle as a Potential Therapeutic Target

24 Oct 2012

Abstract excerpt

Mitochondria play a central role in cell fate after stressors such as ischemic brain injury. The convergence of intracellular signaling pathways on mitochondria and their release of critical factors are now recognized as a default conduit to cell death or survival. Besides the individual processes that converge on or emanate from mitochondria, a mitochondrial organellar response to changes in the cellular...

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PMID: 23093069
DOI: 10.1038/jcbfm.2012.158

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