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Mixture interpretation: Experimental and simulated reevaluation of qualitative analysis.

Legal medicine (Tokyo, Japan) - 1 Mar 2013

Manabe Sho, Mori Yuki, Kawai Chihiro, Ozeki Munetaka, Tamaki Keiji

Abstract excerpt

We present here analytical data using the 15 STR typing (Identifiler) kit regarding heterozygote balance in experimental DNA samples including one or two persons. Surprisingly, the allelic imbalance was observed even in samples consisting of only one person but adequate DNA for the standard protocol. The variance of heterozygote balance was more expanded in two-person mixtures than in one-person samples....

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PMID: 23089142
DOI: 10.1016/j.legalmed.2012.09.001

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