Article
Sheep models of polycystic ovary syndrome phenotype.
Molecular and cellular endocrinology - 5 Jul 2013
Padmanabhan Vasantha, Veiga-Lopez Almudena
Abstract excerpt
Polycystic ovary syndrome (PCOS) is a fertility disorder affecting 5-7% of reproductive-aged women. Women with PCOS manifest both reproductive and metabolic defects. Several animal models have evolved, which implicate excess steroid exposure during fetal life in the development of the PCOS phenotype. This review addresses the fetal and adult reproductive and metabolic consequences of prenatal steroid excess in...
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