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A microfluidic device for rapid screening of chemotaxis-defective Caenorhabditis elegans mutants.

Biomedical microdevices - 1 Apr 2013

Yang Jianping, Chen Zuanguang, Yang Fan, Wang Shuping, Hou Fenghua

Abstract excerpt

Behavioral Caenorhabditis elegans mutants are sought for the purposes of neurobiological research. Until now, large numbers of worms with neuronal defects have been obtained through mutagenesis techniques. However, the existing screening procedures are not only time-consuming and low-throughput, but also tedious and labor-intensive. Therefore, developing a rapid and convenient method to overcome these...

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PMID: 23076545
DOI: 10.1007/s10544-012-9719-7

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