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Article

Competition between influenza A virus genome segments.

PloS one - 1 Jan 2012

Widjaja Ivy, de Vries Erik, Rottier Peter J M, de Haan Cornelis A M

Abstract excerpt

Influenza A virus (IAV) contains a segmented negative-strand RNA genome. How IAV balances the replication and transcription of its multiple genome segments is not understood. We developed a dual competition assay based on the co-transfection of firefly or Gaussia luciferase-encoding genome segments together with plasmids encoding IAV polymerase subunits and nucleoprotein. At limiting amounts of polymerase...

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Identifiers

PMID: 23071819
DOI: 10.1371/journal.pone.0047529
PMCID: PMC3469491

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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