Article
Upper airways microbiota in antibiotic-naïve wheezing and healthy infants from the tropics of rural Ecuador.
PloS one - 1 Jan 2012
Cardenas Paul Andres, Cooper Philip J, Cox Michael J, Chico Martha, Arias Carlos, Moffatt Miriam F, Cookson William Osmond
Abstract excerpt
BACKGROUND: Observations that the airway microbiome is disturbed in asthma may be confounded by the widespread use of antibiotics and inhaled steroids. We have therefore examined the oropharyngeal microbiome in early onset wheezing infants from a rural area of tropical Ecuador where antibiotic usage is minimal and glucocorticoid usage is absent. MATERIALS AND METHODS: We performed pyrosequencing of amplicons of...
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