Article
Residue 75 of interleukin-8 is crucial for its interactions with glycosaminoglycans.
Chembiochem : a European journal of chemical biology - 26 Nov 2012
Nordsieck Karoline, Pichert Annelie, Samsonov Sergey A, Thomas Lars, Berger Christian, Pisabarro M Teresa, Huster Daniel, Beck-Sickinger Annette G
Abstract excerpt
The interactions between regulatory proteins such as interleukin-8 (IL-8) and glycosaminoglycans are of great interest both for the general understanding of regulatory processes in biology and for the development of implant coatings and innovative materials that suppress undesired immune responses and improve wound healing. In previous work, a number of residues of IL-8 that interact strongly with several...
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