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Article

Genetic analysis and SOD1 mutation screening in Iranian amyotrophic lateral sclerosis patients.

Neurobiology of aging - 1 May 2013

Alavi Afagh, Nafissi Shahriar, Rohani Mohammad, Zamani Babak, Sedighi Behnaz, Shamshiri Hosein, Fan Jian-Bing, Ronaghi Mostafa, Elahi Elahe

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease, and the most common in European populations. Results of genetic analysis and mutation screening of SOD1 in a cohort of 60 Iranian ALS patients are here reported. Initially, linkage analysis in 4 families identified a disease-linked locus that included the known ALS gene, SOD1. Screening of SOD1 identified homozygous p.Asp90Ala causing mutations...

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Identifiers

PMID: 23062701
DOI: 10.1016/j.neurobiolaging.2012.09.006

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SOD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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