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Article

Mutation analysis of PFN1 in familial amyotrophic lateral sclerosis patients.

Neurobiology of aging - 1 Apr 2013

Daoud Hussein, Dobrzeniecka Sylvia, Camu William, Meininger Vincent, Dupré Nicolas, Dion Patrick A, Rouleau Guy A

Abstract excerpt

Mutations in the profilin 1 (PFN1) gene, encoding a member of the profilin family of small actin-binding proteins, have been recently reported in patients with familial amyotrophic lateral sclerosis (ALS). In this study we aimed to determine the prevalence of PFN1 mutations by sequencing the coding region of this gene in a cohort of 94 familial ALS patients from France and Quebec. No mutations were identified in...

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Source

Identifiers

PMID: 23062600
DOI: 10.1016/j.neurobiolaging.2012.09.001

Genes

PFN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutation analysis of PFN1 in familial amyotrophic lateral sclerosis patients.PMID 23062600Read ↗

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