The gene in its natural habitat: the importance of gene-trait interactions.

Abstract excerpt

Despite the substantial heritability of nearly all psychological traits, it has been difficult to identify specific genetic variants that account for more than a tiny percentage of genetic variance in phenotypes. Common explanations for this "missing heritability" include massive polygenicity, rare variants, epigenetics, epistasis, and gene-environment interactions. Gene-trait (G × T) interaction is another...

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