Article
Monocytes expression of IL-12 related and IL-10 genes in association with development of colorectal cancer.
Molecular biology reports - 1 Dec 2012
Stanilov Noyko S, Miteva Lyuba D, Dobreva Zlatka G, Jovchev Jovcho P, Cirovski Geo M, Stanilova Spaska A
Abstract excerpt
The main regulator of anti-tumor immune response is the activity of monocytes, suggesting that the produced cytokines may have a prognostic role. This study investigates gene expression of interleukin (IL)-12-related cytokine and IL-10 in stimulated monocytes from colorectal cancer (CRC) patients. Relative quantification of IL-12A, IL-12B, IL-23A and IL-10 mRNA transcripts was performed on the third hours after...
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