Article
The role of nuclear receptors in controlling the fine balance between proliferation and differentiation of neural stem cells.
Archives of biochemistry and biophysics - 1 Jun 2013
Stergiopoulos Athanasios, Politis Panagiotis K
Abstract excerpt
In the central nervous system (CNS) of vertebrates a large variety of cell types are specified from a pool of highly plastic neural stem/progenitor cells (NSCs) via a combined action of extrinsic morphogenetic cues and intrinsic transcriptional regulatory networks. Nuclear receptors and their ligands are key regulators of fate decisions in NSCs during development and adulthood, through their ability to control...
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