Article
Phenotypic and genotypic characterisation of drug-resistant Plasmodium vivax.
Trends in parasitology - 1 Nov 2012
Price Ric N, Auburn Sarah, Marfurt Jutta, Cheng Qin
Abstract excerpt
In this review we present recent developments in the analysis of Plasmodium vivax clinical trials and ex vivo drug-susceptibility assays, as well approaches currently being used to identify molecular markers of drug resistance. Clinical trials incorporating the measurement of in vivo drug concentrations and parasite clearance times are needed to detect early signs of resistance. Analysis of P. vivax growth...
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