Article
The salmonid myostatin gene family: a novel model for investigating mechanisms that influence duplicate gene fate.
BMC evolutionary biology - 8 Oct 2012
Lawson Casey B, Niino Takumu, Hermansen Russell A, Brok-Volchanskaya Vera, Jackson Melissa F, Garikipati Dilip K, Liberles David A, Rodgers Buel D
Abstract excerpt
BACKGROUND: Most fishes possess two paralogs for myostatin, a muscle growth inhibitor, while salmonids are presumed to have four: mstn1a, mstn1b, mstn2a and mstn2b, a pseudogene. The mechanisms responsible for preserving these duplicates as well as the depth of mstn2b nonfunctionalization within the family remain unknown. We therefore characterized several genomic clones in order to better define species and gene...
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