Article
Biophysical and bioinformatic analyses implicate the Treponema pallidum Tp34 lipoprotein (Tp0971) in transition metal homeostasis.
Journal of bacteriology - 1 Dec 2012
Brautigam Chad A, Deka Ranjit K, Ouyang Zhiming, Machius Mischa, Knutsen Gregory, Tomchick Diana R, Norgard Michael V
Abstract excerpt
Metal ion homeostasis is a critical function of many integral and peripheral membrane proteins. The genome of the etiologic agent of syphilis, Treponema pallidum, is compact and devoid of many metabolic enzyme genes. Nevertheless, it harbors genes coding for homologs of several enzymes that typic...
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