Article
Incidence of β-thalassemia carrier on 1495 couples in preconceptional period.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians - 1 Mar 2013
Dell'Edera Domenico, Epifania Annunziata Anna, Malvasi Antonio, Pacella Elena, Tinelli Andrea, Capalbo Antonio, Lioi Maria Brigida, Di Renzo Giancarlo
Abstract excerpt
OBJECTIVE: This research, conducted on 1495 couples in preconceptional period, demonstrates how the study of globular resistance of erythrocytes (GRO) is not a first choice test and not useful as other more accurate tests to identify subjects with β-thalassemia trait. Instead, the complete blood count (CBC) and the evaluation of HbA, HbA2 and HbF by high pressure liquid chromatography (HPLC) are essential....
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