Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Autoantibodies in chronic graft versus host result from cognate T-B interactions.

1 Feb 1990

Abstract excerpt

A chronic graft-versus-host reaction (GVH) induced in nonautoimmune mice causes a syndrome that closely resembles SLE. In this model, donor T cells react against incompatible host Ia structures and generate excessive help, which activates a subpopulation of self-reactive B cells. We have studied whether these self-reactive B cells are activated by direct interaction with alloreactive T cells or by nonspecific...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immunotherapy and Immune Responses
Share to Monoclonal and Polyclonal Antibodies Research
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 2303783
DOI: 10.1084/jem.171.2.503

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Autoantibodies in chronic graft versus host result from cognate T-B interactions.PMID 2303783Read ↗

Donor B Cells in Transplants Augment Clonal Expansion and Survival of Pathogenic CD4+ T Cells That Mediate Autoimmune-like Chronic Graft-versus-Host DiseaseSemantic proximity Read ↗

Donor CD4+ T and B cells in transplants induce chronic graft-versus-host disease with autoimmune manifestationsSemantic proximity Read ↗

B Cells in Chronic Graft-versus-Host DiseaseSemantic proximity Read ↗

The contribution of I-Abm12 to phenotypic and functional alterations among T-cell subsets in NZB mice.Semantic proximity Read ↗

The BM12 mutation and autoantibodies to dsDNA in NZB.H-2bm12 mice.Semantic proximity Read ↗

Antibody to the ligand of CD40, gp39, blocks the occurrence of the acute and chronic forms of graft-vs-host disease.Semantic proximity Read ↗

Developing role of B cells in the pathogenesis and treatment of chronic GVHDSemantic proximity Read ↗

Transfusion of allogenic murine HOD red blood cells preferentially induces low-affinity, short-lived IgG antibodies that are germinal center independentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.