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Malignant peripheral nerve sheath tumours in inherited disease

4 Oct 2012

Abstract excerpt

BACKGROUND: Malignant peripheral nerve sheath tumours (MPNST) are rare tumours known to occur at high frequency in neurofibromatosis 1 (NF1), but may also occur in other cancer prone syndromes. METHODS: The North West Regional Genetic Register covers a population of 4.1 million and was interrogated for incidence of MPNST in 12 cancer prone syndromes. Age, incidence and survival curves were generated for NF1....

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PMID: 23036231
DOI: 10.1186/2045-3329-2-17

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