Associations between a parental history of premature cardiovascular disease and coronary artery calcium and carotid intima-media thickness: the Coronary Artery Risk Development In Young Adults (CARDIA) study.

Abstract excerpt

BACKGROUND: It is unclear if associations between a parental history of premature CVD (pCVD) and subclinical atherosclerosis are attenuated by adjustment for long-term risk factor levels through middle adulthood. DESIGN: Prospective community-based cohort study. METHODS: CARDIA participants who attended the year-20 exam (n = 2283, mean age 45 years) were grouped by pCVD status: maternal only, paternal only, any...

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