Article
In vivo sequence variation in HopZ, a phase-variable outer membrane protein of Helicobacter pylori.
Infection and immunity - 1 Dec 2012
Kennemann Lynn, Brenneke Birgit, Andres Sönke, Engstrand Lars, Meyer Thomas F, Aebischer Toni, Josenhans Christine, Suerbaum Sebastian
Abstract excerpt
The Helicobacter pylori outer membrane protein HopZ is regulated by a phase-variable CT repeat and occurs in two distinct allelic variants. Whole-genome comparisons of isolates from one human volunteer recently provided evidence for in vivo selection for the hopZ ON status. We explored the freque...
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