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Cell death pathways in directly irradiated cells and cells exposed to medium from irradiated cells

1 Oct 2012

Abstract excerpt

PURPOSE: The aim of this study was to compare levels of apoptosis, necrosis, mitotic cell death and senescence after treatment with both direct radiation and irradiated cell conditioned medium. MATERIALS AND METHODS: Human keratinocytes (HaCaT cell line) were irradiated (0.005, 0.05 and 0.5 Gy) using a cobalt 60 teletherapy unit. For bystander experiments, the medium was harvested from donor HaCaT cells 1 hour...

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PMID: 23020735
DOI: 10.3109/09553002.2013.734942

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