Article
Autophagic subpopulation sorting by sedimentation field-flow fractionation.
Analytical chemistry - 16 Oct 2012
Naves Thomas, Battu Serge, Jauberteau Marie-Odile, Cardot Philippe J P, Ratinaud Marie-Hélène, Verdier Mireille
Abstract excerpt
The development of hypoxic areas often takes place in solid tumors and leads cells to undergo adaptive signalization like autophagy. This process is responsible for misfolded or aggregated proteins and nonfunctional organelle recycling, allowing cells to maintain their energetic status. However, it could constitute a double-edged pathway leading to both survival and cell death. So, in response to stress such as...
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