Article
Clinical spectrum and severity of hemolytic anemia in glucose 6-phosphate dehydrogenase-deficient children receiving dapsone.
Blood - 15 Nov 2012
Pamba Allan, Richardson Naomi D, Carter Nick, Duparc Stephan, Premji Zul, Tiono Alfred B, Luzzatto Lucio
Abstract excerpt
Drug-induced acute hemolytic anemia led to the discovery of G6PD deficiency. However, most clinical data are from isolated case reports. In 2 clinical trials of antimalarial preparations containing dapsone (4,4'-diaminodiphenylsulfone; 2.5 mg/kg once daily for 3 days), 95 G6PD-deficient hemizygou...
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