Article
Dilated phase of hypertrophic cardiomyopathy caused by two different sarcomere mutations, treated with surgical left ventricular reconstruction and cardiac resynchronization therapy with a defibrillator.
Internal medicine (Tokyo, Japan) - 1 Jan 2012
Sato Akihiko, Sakamoto Nobuo, Ando Katsuya, Kaneshiro Takashi, Uekita Hironori, Sugimoto Koichi, Yamaki Takayoshi, Kunii Hiroyuki, Nakazato Kazuhiko, Suzuki Hitoshi, Saitoh Shu-ichi, Sato Masatomo, Tamagawa Kazuaki, Arimura Takuro, Kimura Akinori, Takeishi Yasuchika
Abstract excerpt
We herein report the case of a 61-year-old woman with dilated phase of hypertrophic cardiomyopathy (D-HCM) who had been diagnosed with HCM 17 years previously. On admission, her left ventricle (LV) had marked dilation, dyssynchrony with diffuse severe hypokinesis, and ventricular tachycardia. She had two mutations in the cardiac myosin binding protein-C gene, which were suspected to be the causes of the D-HCM. We...
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