Article
Association of melanocortin-4 receptor gene polymorphisms with obesity-related parameters in Malaysian Malays.
Annals of human biology - 1 Jan 2013
Apalasamy Yamunah Devi, Ming Moy Foong, Rampal Sanjay, Bulgiba Awang, Mohamed Zahurin
Abstract excerpt
BACKGROUND: Melanocortin-4 receptor (MC4R) is an important regulator of body weight and energy intake. Genetic polymorphisms of the MC4R gene have been found to be linked to obesity in many recent studies across the globe. AIM: This study aimed to examine the effects of MC4R polymorphisms on obesity parameters, Linkage disequilibrium (LD) pattern and haplotypes in Malaysian Malays. METHODS: The study subjects...
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