Article
The pathogenesis of Hirschsprung's disease-associated enterocolitis.
Seminars in pediatric surgery - 1 Nov 2012
Austin Kelly Miller
Abstract excerpt
Hirschsprung's disease-associated enterocolitis (HAEC) remains the most life-threatening complication in Hirschsprung disease (HD) patients. The pathogenesis of HAEC has not been determined and many hypotheses regarding the etiology of HAEC have been proposed. These include a possible causal relationship between the abnormal enteric nervous system development in HD and the development of enterocolitis. Based on...
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