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Article

A monoclonal antibody against human vitamin-D-binding protein for the analysis of genetic variation in the group-specific component system (Gc).

Human genetics - 1 Jan 1990

Hoffmann R, Braun A, Cleve H

Abstract excerpt

We have developed a murine hybridoma cell line that is stable in secreting a monoclonal antibody (hDBP-1) directed against the group-specific component (Gc) molecule. The hDBP-1 is monospecific for Gc and does not crossreact with human albumin, which has 23% of its amino acid residues identical w...

Topics

Animals
Antibodies, Monoclonal
Blotting, Western
Enzyme-Linked Immunosorbent Assay
Genetic Variation
Humans
Hybridomas
Isoelectric Focusing
Mice
Vitamin D-Binding Protein

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2298449
DOI: 10.1007/BF00208928

Genes

DBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2298449-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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A monoclonal antibody against human vitamin-D-binding protein for the analysis of genetic variation in the group-specific component system (Gc).PMID 2298449Read ↗

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Interaction of the vitamin D-binding protein (group-specific component) and its ligand 25-hydroxy-vitamin D3: binding differences of the various genetic types disclosed by isoelectric focusing.Semantic proximity Read ↗

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