Article
Molecular characterization of direct target genes and cis-acting consensus recognized by quorum-sensing regulator AphA in Vibrio parahaemolyticus.
PloS one - 1 Jan 2012
Sun Fengjun, Zhang Yiquan, Wang Li, Yan Xiaojuan, Tan Yafang, Guo Zhaobiao, Qiu Jingfu, Yang Ruifu, Xia Peiyuan, Zhou Dongsheng
Abstract excerpt
BACKGROUND: AphA is the master quorum-sensing (QS) regulator operating at low cell density in vibrios. Molecular regulation of target genes by AphA has been characterized in Vibrio harveyi and V. cholerae, but it is still poorly understood in V. parahaemolyticus. METHODOLOGY/PRINCIPAL FINDINGS: The AphA proteins are extremely conserved in V. parahaemolyticus, Vibrio sp. Ex25, Vibrio sp. EJY3, V. harveyi, V....
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