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Article

Individual and combined roles of the master regulators AphA and LuxR in control of the Vibrio harveyi quorum-sensing regulon.

Journal of bacteriology - 1 Feb 2013

van Kessel Julia C, Rutherford Steven T, Shao Yi, Utria Alan F, Bassler Bonnie L

Abstract excerpt

Bacteria use a chemical communication process called quorum sensing to control transitions between individual and group behaviors. In the Vibrio harveyi quorum-sensing circuit, two master transcription factors, AphA and LuxR, coordinate the quorum-sensing response. Here we show that AphA regulates 167 genes, LuxR regulates 625 genes, and they coregulate 77 genes. LuxR strongly controls genes at both low cell...

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Identifiers

PMID: 23204455
DOI: 10.1128/JB.01998-12
PMCID: PMC3554009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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