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Article

Predictive role of cytokine gene polymorphisms for the development of femoral head osteonecrosis.

Disease markers - 1 Jan 2012

Samara S, Kollia P, Dailiana Z, Chassanidis C, Papatheodorou L, Koromila T, Malizos K N

Abstract excerpt

INTRODUCTION: Osteonecrosis (ON) is a multifactorial disease that leads to hip destruction. Lately, much focus has been at femoral head preservation with nonsurgical methods. In this study we examined the polymorphisms of IL-1α, IL-1R, IL-1RA, IL-4Rα, IL-1β, IL-12, γIFN, TGF-β, TNF-a, IL-2, IL-4, IL-6 and IL-10 genes for evaluation of their contribution in ON. MATERIAL AND METHODS: DNA was extracted from 112 ON...

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Identifiers

PMID: 22975999
DOI: 10.3233/DMA-2012-0928
PMCID: PMC3810707

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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