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Article

Quick, "imputation-free" meta-analysis with proxy-SNPs.

BMC bioinformatics - 12 Sept 2012

Meesters Christian, Leber Markus, Herold Christine, Angisch Marina, Mattheisen Manuel, Drichel Dmitriy, Lacour André, Becker Tim

Abstract excerpt

BACKGROUND: Meta-analysis (MA) is widely used to pool genome-wide association studies (GWASes) in order to a) increase the power to detect strong or weak genotype effects or b) as a result verification method. As a consequence of differing SNP panels among genotyping chips, imputation is the method of choice within GWAS consortia to avoid losing too many SNPs in a MA. YAMAS (Yet Another Meta Analysis Software),...

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Identifiers

PMID: 22971100
DOI: 10.1186/1471-2105-13-231
PMCID: PMC3472171

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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